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Accomplia is an anti-obesity medication that has struggled some extreme criticism before it was not allowed to enter the markets in both the United States and the United Kingdom.. The main effect that Accomplia establishes is the reduction of appetite which leads to you not wanting to eat as much. By blocking the cannabinoid receptor in the brain Accomplia works as an antagonist on the patients appetite. Throughout numerous studies on the effects Accomplia has on smokers it has been proven to help reduce the want to smoke frequently by blocking receptors in the brain. This has been shown in clinical studies performed by Sanofi-Adventis. Despite most countries drug administrations stating it offers more harmful effects than good the company that created states it can prevent the risk of cardiovascular disease. Accomplia was first marketed by the French pharmaceutical company Sanofi-Aventis , and despite attempts by the company to get Accomplia in circulation throughout the United States it failed due to rejection by the Food and Drug Administration in 2006. The French company were not happy with the initial rejection so they wrote a response, but it was again rejected by the Endocrine and Metabolic Drugs Advisory Committee (EMDAC) in 2007. The committee stated that Accomplia was unsafe for use and the company had not provided sufficient information to prove Accomplia harmless. However in Europe Accomplia was approved in 2006.

